This site has limited support for your browser. We recommend switching to Edge, Chrome, Safari, or Firefox.

MACRENE ACTIVES

Discover the exquisite fusion of expertise, nature, and innovation with Macrene Actives, the brainchild of Dr. Macrene Alexiades, a New York dermatologist with over twenty-five years of experience.

Boasting three Harvard degrees, editorial roles in dermatology journals, and authorship of a textbook, Dr. Macrene's profound knowledge and passion for skincare are reflected in her remarkable line of products.

This exceptional skincare line aims to eliminate the need for clinical treatments, offering maximum results even with the use of just one product.
Designed to make a tangible difference in your skin, Macrene Actives embodies the perfect balance of nature, science, and results.

Nobel Prize-Winning DNA repair research

With a philosophy of deriving the finest ingredients from nature, backed by scientific research, and driven by results, Macrene Actives delivers transformative skincare solutions to combat skin aging and render aesthetic procedures obsolete.

Inspired by Nobel Prize-winning DNA repair research, the groundbreaking skincare line launched with 37 active ingredients and has now evolved to encompass over 50 lipoencapsulated actives, addressing every conceivable skincare concern, packed in different formulas.

Encased in elegant glass packaging, this potent, all-in-one formula is the ultimate minimalist's dream, offering unparalleled efficacy and convenience.

THE SAVIN'SKIN EDIT

Discover our favorite products from Macrene Actives.

Editor's choice

High Performance Face Cream

Macrene Actives

A truly exceptional skincare product. It's the only face cream specifically designed to be applied before serums, ensuring enhanced absorption of its potent actives. Inspired by Nobel Prize-winning DNA repair research, this innovative formula boasts a multitude of awards and features over 50 powerful active ingredients.

Select
Editor's choice

High Performance Lip Filler

Macrene Actives

The Lip Filler is known for its ability to volumize and significantly plump lips without the need for injections. As one of Macrene's bestselling products, it is highly coveted by beauty editors worldwide. Experience the game-changing benefits of this exceptional lip treatment and embrace a fuller, more youthful pout.

Select
Editor's choice

High Performance Tinted Moisturizer

MAcrene Actives

A truly exceptional 2-in-1 formula that simultaneously illuminates and perfects the skin, while providing SPF30 protection. This innovative product not only enhances your complexion but also safeguards it from sun damage, making it an ideal choice for those seeking both beauty and skin health in one convenient step.

Select
Editor's choice

High Performance Eye Cream

Macrene Actives

This exceptional award winning formula effectively combats signs of aging and under-eye circles. It features a blend of 38 plant actives, hyaluronic acid, and peptides, all within a clean, vegan, and fragrance-free formulation. Its expertly crafted composition elevates this eye cream to a league of its own in the realm of skincare.

Select
Editor's choice

High Performance Cleanser

Macrene Actives

This cleanser sets itself apart with its unique formulation, designed to maintain optimal pH and balance for the skin. Not only it gently exfoliates but also hydrates, clarifies, and helps reduce the appearance of fine lines and wrinkles, delivering a comprehensive skincare experience in one exceptional product.

Select

Meet Dr. Macrene Alexiades

Armed with three Harvard degrees, an illustrious dermatology practice, her own skincare research company, and a plethora of prestigious honors and accolades, Dr. Macrene Alexiades, MD PhD FAAD is the ultimate authority in achieving flawless skin.

A trailblazer in the clean beauty realm, Dr. Macrene's dedication to harnessing the power of natural ingredients led to the creation of her award-winning skincare brand, Macrene Actives.
Inspired by Nobel Prize-winning DNA repair research, she developed a collection of transformative products that offer a comprehensive approach to skincare, addressing prevention, restoration, and treatment.

As a visionary leader in the skincare industry, Dr. Macrene continues to weave the tapestry of nature and cutting-edge science, empowering individuals to embrace their most radiant, healthy skin at any age.

Discover our brands

Nobel Prize in 2015 on DNA repair.

Evidence-based active ingredients.

Treat Your Body Like Your Face!

Self-Care for the Active Body.

Wildly Potent Natural Skincare

Voted "The Best Natural Deodorant"

The power of Amazon Jungle

Voted "The Best Lip Balm"

The power of MSM aka "The Beauty Mineral".

Unleash the power of Amazon!

Spellbinding natural color!

The sun looks good on you!

Smart Skincare.

High-Tech Korean Skincare.

The art of "Clean" Beauty!

Clean, skin-centric beauty

Cart

No more products available for purchase

Your cart is currently empty.